More than 86 million Americans suffer from pain. If you are suffering from acute or chronic pain, ask your healthcare provider how Trinity Medical Pharmacy might be able to help. Our Pharmacists will work closely with your physician to determine the origin, severity and regularity of the pain and create a personalized treatment plan for your needs. Compounded medications are applied topically directly to the affected area. The medication is absorbed through the skin, delivering high concentrations of very effective medications to the location of pain. This method may improve pain control, reduce side effects, decrease the need for oral medications and result in fewer drug-drug interactions.
Creams and gels can be formulated to provide high local concentrations of medications at the site of application (i.e. NSAIDs for joint pain, morphine mouthwash for radiation mucositis) and for trigger point application (i.e. combinations of medications for neuropathic pain). Research indicates that topical analgesics create an efficacious option for adjuvant drug therapy with minimal risk of significant systemic absorption and drug-drug interactions. For example, topical administration of NSAIDs offers the advantage of local, enhanced drug delivery to affected tissues with a reduced incidence of systemic adverse effects, such as peptic ulcer disease and GI hemorrhage, seen with oral formulations.
What are Dermatomes?
Dermatomes are areas of the human body that are stimulated by nerve impulses originating in a specific area of your spinal cord. Dermatome areas are clearly defined, and can be tested.What is their purpose? Let’s say you had a burning pain sensation in the upper outer aspect of your thigh. If NO PHYSICAL DAMAGE is found (ex. negative MRI, X-ray, ultrasound), then the problem may be with the sensation that your leg feels. Because we know where it hurts, we can tell which Dermatome it is in, which will lead us to the correct level of the spine in which the injury begins. Therefore, if you apply and massage your custom compound pain cream to the specified Dermatome area, you may experience a reduction in pain.
Transdermal medications utilize the skin or mucosa to facilitate absorption. Studies suggest the there are no great restrictions on the type of drug that can be incorporated into a properly compounded trans-dermal gel, buccal troche, and/or sublingual preparations. Transdermal medications are also a very useful option when patients are unable to take medication orally, and this route of administration can often eliminate the need for injectable therapy. Trans-dermal administration avoids first pass hepatic metabolism, and is an excellent option in patients with fluctuating hepatic function.